문헌고찰 ● 원제:Cannabis for Refractory Psoriasis-High Hopes for a Novel Treatment and a Literature ReviewNima Derakhshan 1Review Curr Clin Pharmacol. 2016;11(2):146-7. doi:10.2174/1574884711666160511150126. ● 출처:Cannabis for Refractory Psoriasis-High Hopes for a Novel Treatment and a Literature Review-PubMed(nih.gov)● 요약건선은 각질세포의 과증식을 특징으로 하는 흔한 피는 질환입니다. 건선의 정확한 병태 생리학은 완전히 밝혀지지 않지만 면역계와 신경계와의 상호 작용이 기본 메커니즘과 가정되어 조사되었습니다. 콜린 효능성 항염증 경로와 엔드 가나비 노이드 시스템 간의 상호 작용은 칸나비 노이드가 항 건선 약에 잠재적으로 추가될 가능성이 있음을 시사하고 있습니다. ● ● 초록 Psoriasis is a common skin disorder characterized by hyper proliferation of keratinocytes. Although the exact pathophysiology of psoriasis is not entirely understood, immune system and its interaction with nervous system have been postulated and investigated as the underlying mechanism. The interaction between these two systems through cholinergic anti-inflammatory pathway and also endocannabinoid system, may suggest cannabinoids as potential addition to antipsoriatic armamentarium.
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